Projects

Externally Funded Projects (Ongoing) in IUCBR & SSH

Sl.No.	Title of the Project	Name of Investigators	Funding agency, year of starting and completing	Amount sanctioned (Rs. In Lakhs)
1.	Development of injectable hydrogel-based delivery system for cartilage tissue repair	Resmi Anand	DST, 2017-2022	101.99
2.	Investigating the role of converging mitochondrial and endolysosomal pathways in the pathogenesis of Parkinson’s disease: Search for novel therapeutic targets	Goutam Chandra	DBT, 2018- 2023	121.10
3.	Dysregulated circulating melatonin in pathophysiological processes in Parkinson’s disease (PD): A study on experimental parkinsonism in animals and in PD patient population from eastern India	Mohanakumar KP	ICMR, 2019-2022	43.64
4.	Neural and genetic correlates of social behaviour in autism spectrum disorder versus attention deficit hyperactivity disorder	Usha Rajamma, G Chandra, Mohanakumar KP	MHRD, SPARC, 2019-2021	74.64
5.	Analysis of Mitochondria-to-Nucleus Epigenetic and Transcriptional Crosstalk in Autism Spectrum Disorder using Cybrid Cell Lines	Usha Rajamma	SERB, 2021-2024	60.00
6.	Ayurveda- A novel perspective into its formulations	Remya VR, Mohanakumar KP	DST, 2018-2021	32.91
7.	Role of mtDNA on ASD-specific changes in serotonergic gene expression	Usha Rajamma	Intl. Society for Neurochemistry, 2018-2019	US$ 9250
8.	Nanoformulated herbal extracts and neuroprotective active constituents against Parkinson’s disease	Rajesh Shenoi; Chinthu V Saji	CSIR, 2019-2022	9.472
9.	Gaze behavior in response to visual image processing generates atypical electrical brain activity in ASD: An investigation towards ASD prognosis using integrated eye tracker-EEG system	Usha Rajamma; Krishna S Nair	ICMR, 2019-2022	14.50
10.	Investigation of possible association of vitamin D and VDR gene with autism spectrum disorder (ASD) phenotype: Validation by developmental vitamin-D deficient rat model	Usha Rajamma, Roana Liz George	ICMR, 2019-2022	14.50
11.	Targeting FOXO- deacetylation mediated autophagy as a therapeutic strategy in Alzheimer’s disease	Goutam Chandra, Rinku Raj Mullasseril	ICMR, 2019-2022	14.50
12.	Engineered dendritic polymer nanoparticles for targeting the mitochondria in neurodegenerative diseases.	Rajesh Shenoi, Mohanakumar KP, Goutam Chandra	DST-SERB, 2019-2023	30.50
13.	In vivo biological evaluation of nano formulated lyso phosphatidyl choline – EPA for neuro-restoration following stroke in experimental animals	Dtr. Goutam Chandra	DHR 2022-2025	42.31
14.	Profiling In Vivo Substrates of Palmitoyl-Protein Thiosterase-1 As A Quest For Novel Therapies For Infantile Neuronal Ceroid Lipofuscinosis	Goutam Chandra, Usha Rajamma, Pramod Kumar	ICMR, Taskforce on Rare Disease. 2020-2023	64.50
15.	Development of a targeted gene editing therapy for the treatment of neuronopathic Gaucher disease	Mohanakumar KP Goutam Chandra, Pramod Kumar	ICMR, Taskforce on Rare Disease. 2020-2023	64.50
16	MTCH1, an upregulated gene in Huntington’s disease animal model: Analysis of its role as a novel target in Huntington’s disease	Dr. Mrudula Mathew	DHR-HRD WSS 2021-2024	42.59
17	Bioengineered Microstrips of dopaminergic neurons as potential cell based therapy for Parkinson Diseases.	Jimna Mohamed Ameer	ICMR-SRF 2022-2025	14.33
18	Neuroprotective effect of hydroxypyridinone-based Iron chelators and their interaction with iron responsive proteins: A therapeutic approach for Parkinson’s disease	Harsha P J	ICMR-SRF 2021-2024	14.33
19	Polymer borne peptides that block the nucleoprotein (NP) and non-structural protein 1 (NS1) of influenza virus as a novel antiviral delivery vehicle	Prabin Pradeep	ICMR-SRF 2021-2024	14.33
20	Investigation on the effect of Mandukaparni (Centella asiatica) Swarasa on Autism Spectrum disorder (ASD) phenotypes using cybrid cell lines and valproic acid induced animal model of ASD	Dr. Anu Raju	ICMR-RA 2021-2024	18.87
21	Personalized Therapeutics for Autism Spectrum Disorder (ASD): Specific SSRI selection employing in-silico and in-vitro generated structural variants of SERT relevant to ASD	Dr. Deepthi Varughese	ICMR-RA 2021-2024	18.87
22	Investigation on Mitochondria-to-Nucleus Epigenetic and Transcriptional Crosstalk in Autism Spectrum Disorder	Merlin Jeejo	CSIR-SRF 2021-2025	22.76
23	Investigation of mitochondrial dysfunction in Autism Spectrum Disorder (ASD) : Evaluation of neuroprotection and reversal of mitochondrial deficits using Ayurvedic medhyarasayana therapy	Dr. Jisha P Janardhanan	AYUSH-SRF 2020-2023	15.2
24	Functional EEG microstates: A potential electrophysiological biomarker of emotion dysregulation in attention deficit hyperactivity disorder	Dr. Angel Anna Zacharia	ICMR – RA 2022-2025	19.04
25	Role of parkin and its substrate zinc finger protein 746 in Parkinson’s disease	Safreena N	CSIR- JRF 2021-2023	22.76
26	Daphnia as a model organism for investigating parkinsons diseases biology	Neethumol OP	UGC- JRF 2021-2024	12.65
27	Role of astrocyte secretion in pathogenesis of Attention deficit hyperactive disorder (ADHD)	Dr Sreetama Sen Chandra	DST-WOS-A 2023-2026	28.30